Producers that plan to use artificial insemination as part or all of this upcoming spring breeding season should start their preparations soon. One synchronization protocol for replacement beef heifers involves the feeding of an additive, and the feed must be ordered and delivered at the proper time. Melengestrol acetate (MGATM) is a feed additive commonly used in heifer feedlot rations to block the cycling activity of heifers. Melengestrol acetate is a synthetic progestin that has "progesterone-like" activity. When fed for a short period of time and then removed from the diet, the sudden absence of progestin tends to allow a large percentage of heifers to exhibit heat together. Compared to normal heats, fertility at this first heat after MGATM removal has been reduced. Subsequent heats will return to normal fertility. Armed with this knowledge, researchers have outlined an estrous synchronization protocol using MGATM and a prostaglandin injection. This program calls for the feeding of melengestrol acetate at the rate of 0.5 milligram per head per day for 14 days. After 14 days, MGATM is removed from the feed. Most of the heifers will then exhibit heat over the next 8 days. Nineteen days after the MGATM feeding has stopped, each female is injected with prostaglandin to interrupt the next cycle. For the next six days, females are bred following detected standing heat. (See time line below).
Research at several experiment stations has indicated that this method has induced some non-cycling replacement heifers to begin cycling, thereby increasing the percentage of those cattle bred early in the insemination season. An important consideration is that the MGATM/prostaglandin synchronization program must be started 33 days before the start of the breeding season. This means that prior planning must be done to assure that the feed containing MGATM is prepared and ready to feed five weeks before the date of the first breeding. This synchronization method is designed to work with replacement heifers. Other synchronization methods for replacement heifers are available. This method requires the earliest planning to be certain that the feed is prepared and delivered in time.
Time line for MGATM/prostaglandin synchronization method for heifers
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Day 0 |
Day 14 |
Day 33 |
Days 33 to 39 |
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Start MGATM Feed |
Stop MGATM Feed
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Inject with prostaglandin |
Heat detect and breed AI |
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Source: Glenn Selk, OSU Extension Cattle Reproduction Specialist