On September 29, the FDA issued a revised Guidance for Industry #120, titled Veterinary Feed Directive Regulation Questions and Answers.” The revised guidance includes minor changes to the draft version issued in June. FDA also released a list of states that have adequate veterinarian-client-patient-relationship (VCPR) requirements for compliance with the VFD rules, and which currently need to defer to the federal VDPR definition.
Changes to the veterinary feed directive (VFD) VFD rule will bring the use of medically important feed-grade antibiotics under the oversight of veterinarians by January 1, 2017.
The new VFD rule actually takes took effect week on Oct. 1, 2015, affecting the use of three antibiotics currently classified as VFD drugs. Those are Avilamycin, Florfenicol and Tilmicosin. Of those, only Tilmicosin is used as a feed-grade drug in cattle.
As of January 1, 2017 the list of VFD drugs will expand to include all medically important antibiotics used in feed for prevention, control and treatment of disease. Cattle drugs affected at that time include Neomycin, Tylosin, Virginiamycin, Chlortetracycline and Oxytetracycline. Over-the-counter sales of those drugs will no longer be allowed, and producers will need to work through their veterinarian to obtain a VFD order.
The revised guidance 120 includes an additional question and answer about VFD authorization for pioneer and generic drugs, and clarification on how a veterinarian can authorize or limit the use of a VFD drug when used in combination with over-the-counter drugs.
Also on September 29, the FDA released a list of states that either have or do not have veterinarian-client-patient-relationship (VCPR) requirements, compatible with the federal VCPR definition, for use in issuing VFD orders. The new VFD rules specify that veterinarians can issue VFD orders only within the context of a valid VCPR. If applicable VCPR requirements as defined by a state do not include the key elements of a valid VCPR as defined in the Code of Federal Regulations, the veterinarian must issue the VFD in the context of the federal definition. The list shows that, as of September 29th, 28 states have suitable VCPR requirements, while 22 states and the District of Columbia do not have VCPR requirements that match the federal standards.