"Doctor, there's a veterinarian on the line who wants to talk to you about some blisters he's seeing in a group of pigs."

That doesn't sound like a big deal, right?  But if you are a regulatory veterinarian - tasked with protecting animal populations from incursions of serious diseases - this is a call you dread taking. 

The reason for the anxiety has to do with the most feared of foreign animal diseases - Foot and Mouth Disease (FMD). 

The U.S. has not seen FMD since 1929. It is among the most contagious diseases known to the animal world, affecting cloven-hoofed animal species. Were it to enter our livestock herds, it would devastate not just the livestock economy, but likely the entire U.S. economy as well. 

When state and federal veterinarians have trouble sleeping at night, they're probably having a nightmare about FMD in their backyard.

The main effect of FMD infection is to cause blisters, or vesicles, in the mouth, tongue and on the coronary band (where the hoof meets the skin) of the animal. 

Affected animals can't eat, drink or walk without pain. Often, by the time the animal is examined, the blisters have broken, leaving raw sores in the mouth and on the tongue. 

Vesicular Stomatitis & Seneca Valley Virus Look like, but are not FMD

This summer, we've seen the emergence of two infectious livestock diseases that create vesicles similar to FMD. They create problems for the affected animals, but they are not usually debilitating. 

Perhaps the biggest problem with these diseases is that they can look just like FMD. When these diseases pop up, each one has to be treated like a foreign animal disease until FMD can be ruled out. 

The first of these to show up in South Dakota this summer was Vesicular Stomatitis. 

Vesicular Stomatitis has mainly affected horses - which is helpful from a regulatory standpoint since horses don't get FMD - but can also affect cattle. 

Vesicular Stomatitis pops up every year, but it's typically been a problem only in southwestern states. This year, it crept as far north as western South Dakota, affecting horses as well as some cattle. 

The disease is caused by a virus spread by biting flies and gnats, so it dies out after a good freeze. 

Affected farms are quarantined because animals can spread it directly between themselves, or via a person using contaminated tack or clothing. 

Then there was the discovery of Seneca Valley Virus. 

First noticed in show pigs and finisher pigs, Seneca Valley Virus has now been observed in breeding stock as well. We've had it here in South Dakota. 

Affected pigs develop blisters on their snouts and feet. Accordingly, lameness has been a clinical feature of Seneca Valley Virus infection.    

Unlike Vesicular Stomatitis, no one had an inkling Seneca Valley Virus was a potential pathogen. 

It was an obscure virus found contaminating a lab culture back in 2002. Now it's emerged as a pathogen. We know very little about how it's transmitted between animals or farms, but we're learning more each day. 

Seneca Valley Virus is yet another example of how some viruses previously considered rare and harmless can emerge to create restless nights for those of us trusted to protect animal health. 

Viruses like these are the reason veterinary labs and universities need to stay up to date with the ability to detect and research these emerging pathogens. 

Vesicular Stomatitis and Seneca Valley Virus aren't Foot and Mouth Disease, thank goodness. But danger still exists from their presence. 

The worry is that animal owners and veterinarians might become complacent and ascribe these events to something harmless, not bothering to rule out FMD. 

Foot and Mouth Disease remains a threat - it's prevalent worldwide and could be just a plane ride away. If it ever gets here, time is of the essence if there's any hope of containing it. 

Even though the chances are slim, it's important enough that when animals show up with these signs, you should call your veterinarian right away.